Metabolite相关论文
肠道是营养成分消化吸收的主要场所,肠道菌群参与了机体的能量存储、代谢、免疫等活动,在维持机体健康及诱导肿瘤发生等方面具有重要......
Comparative metabolomics provides novel insights into the basis of petiole color differences in cele
Plant metabolites are important for plant development and human health. Plants of celery (Apium graveolens L.) with diff......
Metabonomics delineates allergic reactions induced by Shuang-huang-lian injection in rats using ultr
Shuang-huang-lian Injection (SHLI) is the first successfully developed drug from traditional Chinese medicine (TCM) powd......
Mangiferin (1,3,6,7-tetrahydroxyxanthone-C-2-β-D-glucoside) has been isolated from the leave of Mangifera indica L.and ......
Quorum sensing related gene ygaG affects the production of metabolites in Klebsiella pneumoniae from
Klebsiella pneumoniae is as an industrial important host for the production of compounds such as 1,3-propanediol,2,3-but......
Concentration level of antituberculous drugs in the focus of spinal tuberculosis has been reported....
Application of HPLC-MS metabolomics to the characterization and possible detection of renal cell car
Objective: Renal cell carcinoma (RCC) is a common malignant tumor of the urinary system.Early detection is the effective......
Application of HPLCMS metabolomics to the characterization and possible detection of renal cell carc
Objective: Renal cell carcinoma(RCC)is a common malignant tumor of the urinary system.Early detection is the effective w......
Metabolic and proteomic profiling of metabolic pathways associated with improvement in heat toleranc
Heat is a major factor limiting growth of C3 grass species.Elevated CO2 may mitigate the adverse effects of heat stress ......
Simultaneous determination of ulipristal acetate and its main active metabolite, N-desmethyl ulipris
A simple and sensitive UPLC-MS/MS method has been developed to simultaneous quantify ulipristal acetate (UPA) and its ma......
Characterization of geniposide metabolites in rats using ultra-high-performance liquid chromatograph
Geniposide(genipin 1-O-glucose),which is one of the major bioactive constituents isolated from Fructus Gardeniae,possess......
Effects of Liuwei Dihuang decoction and its compatible prescriptions on urine metabolites of cortiso
Aim: To investigate the effects of Liuwei Dihuang decoction (LW) and its San-bu (three tonics) and San-xie (three elimin......
Simultaneous determination of pirfenidone and its metabolite in human plasma by liquid chromatograph
A simple and rapid analytical method was developed and validated for the simultaneous determination of pirfenidone and i......
Objective There are sufficient evidences to suggest that trans-resveratrol (T-Res) is effective at tumor inhibition in d......
A bacteria strain,YW6,capable of utilizing monocrotophos(MCP)as the sole carbon and nitrogen source for growth was isola......
Determination of Metabolites and Processes Related Impurities for Radiomedicines by HPLC-Tandem Mass
RadioPharmaceutical Characterization Laboratory (RPCL) of Institute of Nuclear Energy Research (INER) has been devoting ......
Determination of allopurinol and oxypurinol in human plasma and urine by liquid chromatography-tande
Allopurinol is used widely for the treatment of gout,but its pharmacokinetics is complex and some patients show hypersen......
Simultaneous determination of pirfenidone and its metabolite in human plasma by liquid chromatograph
A simple and rapid analytical method for the simultaneous determination of pirfenidone and its metabolite,5-carboxy-pirf......
Analysis of the Constituents in Rat Serum after Oral Administration of Fufang Zhenzhu Tiaozhi Capsul
A rapid and sensitive UPLC/Q-TOF-MS method has been established for analysis of the constituents in rat serum after oral......
The association among exposure of bisphenol A,genetic polymorphism of metabolic enzyme and urinary m
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Capillary Electrophoresis-Mass Spectrometry Characterization:Protein & Metabolite Nanoparticle Coron
Capillary Electrophoresis(CE)has been applied to nanomaterial research for the past 30 years; typically this work has fo......
Perturbance on the gut microbiome and its metabolic profile by environmental contaminants:A comparis
Mercury (Hg) is a widespread environmental toxicant1.Among the various forms of Hg,methylmercury (MeHg) can cause neurol......
Metabolite discovery and identification is an important task in early drug discovery studies.High performance liquid chr......
Determination and analysis of toluene diisocyanate metabolites in mice using gas chromatography-mass
In this research we use gas chromatography-mass spectrometry (GC-MS) to determine metabolites of toluene diisocyanate (T......
Solid phase extraction and bioanalysis of CpG oligonucleotides 107 (CpG ODN107) and it’s metabolites
CpG oligodeoxynucleotide 107 (CpG ODN107) is a novel radiosensitizer for glioma.Herein,a novel and sensitive reversed ph......
Simultaneous determination of aspirin,paracetamol,and their metabolites by HI/SAX capillary liquid c
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Intestinal microbiota participates in nonalcoholic fatty liver disease progression by affecting inte
Nonalcoholic fatty liver disease(NAFLD)is a chronic liver disease with a pathogenesis that has not been fully elucidated......
Ursolic acid reduces hepatocellular apoptosis and alleviates alcohol-induced liver injury via irreve
Alcoholic liver disease (ALD) is one of the pathogenic factors of chronic liver disease with the highest clinical morbid......
[Objectives]The differences in secondary metabolites of Herba Polygoni Chinensis from Guangxi were analyzed,in order to ......
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SELECTION OF CANDIDATE RADIATION BIOMARKERS IN THE SERUM OF RATS EXPOSED TO GAMMA-RAYS BY GCTOFMS-BA
In the study, gas chromatography /time-of-flight mass spectrometry (GC/TOFMS) techniques coupled with principal comp......
Modulation of Metabolite and Nutrient Clusters in Wild Type and Genetically Altered Tomatoes is Diff
We are faced with three major challenges in the third millennium: produce more(nutritious)food to meet the demand of......
IN VIVO ~1 H MAGNETIC RESONANCE SPECTROSCOPY IN EVALUATION OF HEPATOCELLULAR CARCINOMA AND ITS EARLY
Objective To investigate the value of in vivo proton magnetic resonance spectroscopy (MRS) in the assessment of hepatoce......
AIM:To evaluate the utility of serum and urine metabolomic analysis in diagnosing and monitoring of inflammatory bowel d......
选用32头经产奶牛,根据泌乳期、上个泌乳期305d产奶量和预产期,采用随机区组设计分为4组,对照组饲喂基础日粮,处理1、2、3组分别在基础......
<正> DDT-prostrate cockroaches release, from the nerve cord into the haemolymph, a neurotoxin which is not DDT or its me......
核糖开关是一类自然界中天然存在的适配子,通过结合小分子代谢物调控基因的表达。它位于特定的mRNA非编码区,可以不依赖任何蛋白质因......
Evaluation of quantitative variation of secondary metabolites in Bergenia ciliata(Haw.)using high pe
Dear Editor:Therapeutically active metabolite contents in a medicinal plant vary in nature,which may impact on its thera......
Objective To evaluate the bioavailability and bioequivalence of oseltamivir capsule in Chinese health male volunteers.Me......
AIM: To evaluate the effectiveness of thiopurines in maintaining steroid-free remission in routine clinical practice.MET......
A new polyketide synthase nonribosomal peptide synthetase hybrid metabolite from plant endophytic fu
A new polyketide synthase–nonribosomal peptide synthetase(PKS–NRPS) hybrid metabolite, named pericoannosin B(1), was i......
A Randomized, Controlled, Single-Blind Trial of Leflunomide in the Treatment of Rheumatoid Arthritis
The efficacy and safety of leflunomide (LEF) in the treatment of rheumatoid arthritis (RA) were evaluated and the compar......
The detection of protein/small molecule interactions plays important roles in drug discovery and protein/metabolite inte......
In this review, we highlight the latest development of multi-channel microfluidic chip-mass spectrometry(chip-MS) in cel......
医学上临床检查一般都是在空腹时采血标本进行测定,但最近对餐后数值的关注日益增多,特别是餐后血糖的上升、胰岛素动态变化等被用......
AIMTo identify metabolic signatures in urine samples from healthy and inflammatory bowel disease(IBD)children.METHODSWe ......
Dietary exposure to di-isobutyl phthalate increases urinary 5-methyl-2′-deoxycytidine level and affe
Phthalates are a large family of ubiquitous environmental pollutants suspected of being endocrine disruptors. Epidemiolo......